Gene interactions and pathways from curated databases and text-mining

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CPOX — IL12A

Text-mined interactions from Literome

Inada et al., J Immunotoxicol 2011 : Endogenous COX inhibition with propofol, as well as with the selective COX-2 inhibitor, NS-398, did not affect IL-12 and IL-10 production from DC
Thakur et al., Journal of translational medicine 2013 (Pancreatic Neoplasms) : Reduced accumulation of MDSC was accompanied by significantly lower levels of COX2 ( p < 0.0048 ), PGE2 ( p < 0.03 ), and their downstream effector molecule Arginase-1 ( p < 0.01 ), and significantly higher levels of TNF-a, IL-12 and chemokines CCL3, CCL4, CCL5, CXCL9 and CXCL10 under aATC induced Th1 cytokine enriched microenvironment