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CDK5 — NEUROD6

Text-mined interactions from Literome

Lefèvre et al., J Comp Neurol 2002 (Nerve Degeneration) : Each of these inhibits CDK1, CDK2, and CDK5 ; CDK1 and CDK2 are involved in cell proliferation, whereas CDK5 is involved in neuronal differentiation
Fu et al., J Neurochem 2002 : Taken together, our results demonstrated that NT2 cells provide a good in vitro model system to examine signaling pathways involved in the regulation of Cdk5 activators and to elucidate the functional roles of Cdk5 in neuronal differentiation
Song et al., J Biol Chem 2005 : In agreement with the role of p35-Cdk5 in neuronal differentiation , small interfering RNA targeting Cdk5 abrogate the IFN-gamma induced neurite outgrowth
Cicero et al., J Neurosci 2005 : In the present study, we show that loss of Cdk5 leads to both failure of neuronal differentiation and loss of cell cycle control ... These data indicate that Cdk5 is necessary for both neuronal differentiation and cell cycle inhibition
Sumrejkanchanakij et al., Biochem Biophys Res Commun 2006 (Neuroblastoma) : The regulation of D-type cyclin dependent kinase activity is critical for neuronal differentiation and apoptosis
Darbinian et al., J Cell Physiol 2008 : As p35, by associating with Cdk5 , phosphorylates several neuronal proteins including neurofilaments and plays a role in neuronal differentiation and survival, we examined kinase activity of p35 complexes obtained from cells expressing Tat