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FLT1 — SETD2
Text-mined interactions from Literome
Tipoe et al., Respir Physiol Neurobiol 2003
(Anoxia) :
Hence,
HIF-1 may
activate the expression of VEGF and
VEGFR-1 in the CB and the expression of VEGF in the chemoreceptors may play a paracrine role in the vascular remodeling during chronic hypoxia
Okuyama et al., J Biol Chem 2006
:
Thus, loss-of-function and gain-of-function approaches demonstrated that
HIF-1 activity is
necessary and sufficient for basal and hypoxia induced
VEGFR1 expression in bone marrow derived MSC
Hwang et al., Yonsei Med J 2013
:
Induction of
HIF-1a and TUBB3 in AGS is
VEGFR-1 mediated and PlGF dependent
Hinkel et al., Curr Vasc Pharmacol 2013
(Constriction, Pathologic...) :
Hif-1a , a master regulator of ischemia-responsive gene induction,
controls pro-angiogenic gene expression of VEGF-A,
flt-1 , IGF-1 and erythropoietin, rendering its overexpression an attractive tool for therapeutic neovascularization