Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Sanchez et al., J Clin Invest 2004 : Since this maturation in response to leptin requires prohormone processing, we hypothesized that leptin might regulate hypothalamic PC1 and PC2 expression, ultimately leading to coordinated processing of prohormones into mature peptides
Nillni et al., Endocrinology 2007 (Obesity) : Because biosynthesis of mature peptides in response to leptin requires prohormone processing, it is hypothesized that leptin might regulate hypothalamic PC1/3 and PC2 expression, ultimately leading to coordinated processing of prohormones into mature peptides