Ichinohe et al., J Exp Med 2009
(Orthomyxoviridae Infections) :
Although NLRP3 was required for inflammasome activation in certain cell types, CD4 and CD8 T cell responses, as well as mucosal IgA secretion and systemic IgG responses, required ASC and caspase-1 but not NLRP3
Roemeling-van Rhijn et al., Frontiers in immunology 2013
:
The ability of ASC to inhibit anti-CD3/CD28 stimulated CD4 ( + ) and CD8 ( + ) T cell proliferation was not hampered by hypoxia