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IL6 — LBP

Text-mined interactions from Literome

Li et al., Chin J Traumatol 2003 : The level of plasma endotoxin peaked at 1 h after LPS injection, then declined, but was still higher than that of the normal group at 12 h ; intrahepatic expression of LBP mRNA and plasma LBP increased with time after LPS stimulation ; TNF-alpha and IL-6 in plasma increased with upregulation of LBP expression ; there were significant differences between the normal group and endotoxemia groups ( P < 0.05 )
Hallatschek et al., Eur J Immunol 2004 : We show here that TGF-beta 1, in a dose dependent fashion, is able to inhibit LBP transcript accumulation and LBP protein synthesis induced by IL-6 , IL-1 beta and dexamethasone in hepatoma cell lines
Ren et al., J Periodontal Res 2005 : The present in vitro study aimed to investigate the possible effect of LBP and E. coli LPS interaction on the expression of cellular LPS receptors and IL-6 by human gingival fibroblast
Blais et al., Invest Ophthalmol Vis Sci 2005 : In a dose-dependant manner, tear CD14 and LBP mediated the secretion of interleukin (IL)-6 and IL-8 by corneal epithelia cells when challenged with LPS
Regueiro et al., Eur Respir J 2009 : IL-6 , IL-1beta and cigarette smoke condensate induced the expression of LBP and CD14 by airway epithelial cells
Yang et al., Curr Drug Metab 2012 : SOCS-3, CRP, and LBP were extensively induced by IL-6 , with maximal induction observed at 2 ( SOCS-3 ) and 12 hrs ( CRP ; LBP ), demonstrating that the cultured human hepatocytes responded to IL-6 treatment
Grube et al., J Biol Chem 1994 (Carcinoma, Hepatocellular...) : We found that human primary hepatocytes synthesize LBP and that the synthesis is up-regulated by interleukin (IL)-6 ... To examine this phenomenon in more detail, we evaluated the capacity of IL-6 , IL-1, and tumor necrosis factor to induce LBP synthesis in HepG2 cells in the presence or absence of dexamethasone ... IL-6 induced LBP synthesis
Wan et al., Infect Immun 1995 : The induction of LBP by IL-6 or LPS was attenuated by dexamethasone ... In contrast to IL-6 and LPS, in the presence of 10 ( -6 ) M dexamethasone, IL-1 and tumor necrosis factor (TNF) led to maximal LBP mRNA induction levels, 4.7- and 3.8-fold, respectively, suggesting that IL-6 and LPS stimulate LBP expression by mechanisms different from those of IL-1 and TNF
Schumann et al., Mol Cell Biol 1996 (Carcinoma, Hepatocellular...) : We show that induction of LBP expression is transcriptionally regulated and is dependent on stimulation with IL-1beta, IL-6 , and dexamethasone
Amura et al., J Immunol 1997 : We have investigated the effects of human LPS binding protein (LBP) and human bactericidal/permeability increasing protein ( BPI ) on LPS dependent activation of mouse thioglycolate elicited peritoneal macrophages in vitro, in comparison with human PBMCs. Confirming earlier published studies, BPI inhibited, and LBP enhanced , the ability of LPS to stimulate PBMC production of the cytokines TNF-alpha and IL-6
Kirschning et al., Immunobiology 1997 : IL-6 alone induces LBP significantly, whereas IL-1 beta mainly increases the IL-6 effect when applied in combination