Chen et al., Cell 1999
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SNARE complex formation is triggered by Ca2+ and drives membrane fusion
Merz et al., J Cell Biol 2004
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Here, we show that trans-SNARE interactions promote the release of Ca2+ from the vacuole lumen
Pang et al., J Neurosci 2006
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Using knock-in mice that carry aspartate-to-asparagine substitutions in a Ca2+ binding site of synaptotagmin-1 ( the D232N or D238N substitutions ), we now show that the D232N mutation dramatically increases Ca2+ dependent SNARE complex binding by native synaptotagmin-1, but leaves phospholipid binding unchanged
Tahara et al., J Biol Chem 1998
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Most notably, CV SNARE complexes are disrupted in response to [ Ca2+ ] free that trigger maximal fusion