Abbas et al., Free Radic Biol Med 2009
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Moreover, addition of exogenous TNF allowed the recovery of full PRX5 expression in both MyD88 ( -/- ) and TNF ( -/- ) cells stimulated with IFN-gamma, suggesting that basal TNF produced in an MyD88 dependent manner contributes to PRX5 induction
Lu et al., J Bone Miner Res 2011
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Activation of Prx1 by TNF may contribute to reduced bone formation in inflammatory arthritis, menopause, and aging