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MICE — TP53

Text-mined interactions from Literome

Iwakuma et al., Oncogene 2007 (Disease Models, Animal...) : Mice with mutations at post-translational modification sites exhibit subtle effects on p53 activity and tumor development, indicating a fine tuning mechanism of p53 activity in vivo
Terzian et al., Genes Dev 2008 (Neoplasm Metastasis...) : Mice lacking Mdm2 or p16INK4a stabilized mutant p53 , and revealed an earlier age of tumor onset than p53 mutant mice and a gain-of-function metastatic phenotype