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BLM — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: BLM — TP53 Garkavtsev et al., Oncogene 2001*
• IRef Bind Interaction: BLM — TP53 Yang et al., J Biol Chem 2002*
• IRef Bind Interaction: BLM — TP53 Restle et al., Oncogene 2005*
• IRef Bind_translation Interaction: BLM — TP53 (unspecified method) Yang et al., J Biol Chem 2002*
• IRef Bind_translation Interaction: BLM — TP53 (coimmunoprecipitation) Restle et al., Oncogene 2005*
• IRef Bind_translation Interaction: BLM — TP53 (two hybrid) Garkavtsev et al., Oncogene 2001*
• IRef Bind_translation Interaction: BLM — TP53 (affinity chromatography technology) Yang et al., J Biol Chem 2002*
• IRef Bind_translation Interaction: BLM — TP53 (coimmunoprecipitation) Yang et al., J Biol Chem 2002*
• IRef Bind_translation Interaction: BLM — TP53 (experimental interaction detection) Yang et al., J Biol Chem 2002*
• IRef Biogrid Interaction: BLM — TP53 (physical association, affinity chromatography technology) Sengupta et al., J Cell Biol 2004*
• IRef Biogrid Interaction: BLM — TP53 (colocalization, imaging technique) Sengupta et al., J Cell Biol 2004*
• IRef Biogrid Interaction: BLM — TP53 (physical association, affinity chromatography technology) Wang et al., J Biol Chem 2001*
• IRef Biogrid Interaction: BLM — TP53 (colocalization, imaging technique) Wang et al., J Biol Chem 2001*
• IRef Biogrid Interaction: BLM — TP53 (direct interaction, pull down) Wang et al., J Biol Chem 2001*
• IRef Biogrid Interaction: BLM — TP53 (physical association, affinity chromatography technology) Garkavtsev et al., Oncogene 2001*
• IRef Biogrid Interaction: BLM — TP53 (direct interaction, two hybrid) Garkavtsev et al., Oncogene 2001*
• IRef Biogrid Interaction: BLM — TP53 (physical association, affinity chromatography technology) Yang et al., J Biol Chem 2002*
• IRef Biogrid Interaction: BLM — TP53 (direct interaction, pull down) Yang et al., J Biol Chem 2002*
• MIPS CORUM MSH2/6-BLM-p53-RAD51 complex: MSH2/6-BLM-p53-RAD51 complex complex (BLM-MSH2-MSH6-RAD51-TP53) Yang et al., Oncogene 2004*
• IRef Corum Interaction: Complex of 11 proteins (association, anti bait coimmunoprecipitation) Yang et al., Oncogene 2004*
• IRef Hprd Interaction: Complex of 17 proteins (in vivo) Yang et al., Oncogene 2004*
• IRef Hprd Interaction: Complex of TP53-BLM-TP53BP1-BLM-TP53-TP53BP1-TP53BP1-BLM-TP53 (in vivo) Sengupta et al., J Cell Biol 2004*
• IRef Hprd Interaction: TP53 — BLM (in vivo) Wang et al., J Biol Chem 2001*, Garkavtsev et al., Oncogene 2001*
• IRef Hprd Interaction: TP53 — BLM (in vitro) Wang et al., J Biol Chem 2001*, Garkavtsev et al., Oncogene 2001*
• IRef Intact Interaction: Complex of 29 proteins (association, anti tag coimmunoprecipitation) Coffill et al., EMBO Rep 2012
• IRef Ophid Interaction: BLM — TP53 (aggregation, confirmational text mining) Garkavtsev et al., Oncogene 2001*
• IRef Ophid Interaction: BLM — TP53 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Sengupta et al., EMBO J 2003 (Bloom Syndrome) : However, BLM was required for efficient localization of either wild-type or mutated ( Ser15Ala ) p53 to these foci and for physical association of p53 with RAD51
Kaneko et al., Mol Med Report 2011 (Bloom Syndrome) : BLM deficiency causes the up-regulation of p53 , double-strand break and apoptosis, which are likely observed in irradiated control cells
Cianfarani et al., Eur J Clin Invest 1998 (Chromosome Fragility) : BLM significantly increased both percentage DC and percentage CA and p53 expression ( P < 0.01 ) ... The spontaneous and BLM induced expression of p53 was unaffected by GH, whereas it was significantly increased by IGFs ( P < 0001 )