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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to MAPK1

EP300 — MAPK1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: EP300 → MAPK1 (increases, MAPK1 Activity, EP300 Activity) Goel et al., Mol Cell Biol 2003*
    Evidence: Furthermore, oncogenic HER2/Neu, which induces phosphorylation and thereby activation of ER81, was less able to activate acetylation-deficient ER81 mutants, indicating that both acetyltransferase and protein kinase-specific regulatory mechanisms control ER81 activity. Importantly, HER2/Neu overexpression stimulates the ability of p300 to acetylate ER81, likely by inducing phosphorylation of p300 through the Ras-->Raf-->mitogen-activated protein kinase pathway.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *