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ADO — AKT3

Text-mined interactions from Literome

Sedding et al., Circ Res 2009 : Mechanistically, c3Ado prevented FCS induced Ras carboxyl methylation and membrane translocation and activity by inhibiting isoprenylcysteine carboxyl methyltransferase and reduced FCS induced extracellular signal regulated kinase ( ERK ) 1/2 and Akt phosphorylation in a dose dependent manner ... c3Ado prevented dilation induced Ras activation, as well as ERK1/2 and Akt phosphorylation in vivo
Dennison et al., Blood 2010 (Lymphoma, Mantle-Cell) : In the current study, the preclinical efficacy of 8-NH ( 2 ) -Ado and its resulting effects on Akt/mTOR and extracellular-signal regulated kinase signaling were evaluated using 4 MCL cell lines, primary MCL cells, and normal lymphocytes from healthy donors