Rabini et al., J Clin Endocrinol Metab 1999
(Diabetes Mellitus, Type 1) :
IDDM LDL significantly increased the platelet aggregating response to ADP, cytosolic Ca2+ concentrations, and plasma membrane Ca2+-ATPase activity and significantly reduced NOS activity and platelet membrane Na+/K+-ATPase activity compared with those of platelets incubated in buffer or cells incubated with control LDL
Guan et al., Chin Med J (Engl) 2003
(Arteriosclerosis) :
The ox-LDL can significantly increase the expression of ICAM-1 and inhibit the expression of NO and NOS in a dose dependent manner
Dong et al., J Cell Mol Med 2009
:
Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase Hamilton et al., J Clin Invest 1995
:
The cooperative effects of IFN gamma and LPS on the expression of the inducible nitric oxide synthase gene were suppressed by oxidized LDL while the antagonistic effect of IFN gamma on LPS induced expression of the TNF receptor type II mRNA was not altered