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IGF1 — VTN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Maile et al., Mol Endocrinol 2006
:
We have shown that
vitronectin (Vn) binding to a cysteine loop sequence within the extracellular domain of the beta3-subunit ( amino acids 177-184 ) of alphaVbeta3 is
required for the positive effects of Vn on
IGF-I signaling
Shinohara et al., International journal of dentistry 2012
:
Effect of
vitronectin bound to
insulin-like growth factor-I and insulin-like growth factor binding protein-3 on porcine enamel organ derived epithelial cells
Doerr et al., J Biol Chem 1996
(Breast Neoplasms) :
We conclude that : 1 ) IGF-I stimulates migration of these two cell types through the IGF-I receptor ; 2 ) interaction of
vitronectin with the alpha v beta 5 integrin or collagen with the alpha 2 beta 1 integrin is
necessary for the complete
IGF-I response in MCF-7 cells, and 3 ) because migration represents an in vitro model for metastatic spread, integrins, extracellular matrix proteins, and IGF-I may play coordinated roles in the metastasis of breast cancer in vivo
Jones et al., Prog Growth Factor Res 1995
(Breast Neoplasms) :
IGF-I stimulation of SMC migration
requires the presence of either 0.2 % serum or
vitronectin , because of a requirement for ligand binding by the alpha V beta 3 integrin ( vitronectin receptor )