Gene interactions and pathways from curated databases and text-mining

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IL4 — SYT1

Text-mined interactions from Literome

Schaffer et al., J Immunol 1999 : Electrophoretic mobility shift assays showed that p50/p65/c-Rel and STAT-6 are effectively induced by CD40L and IL-4 , respectively, and bind to specific DNA motifs within the ECS
Ember et al., J Gen Virol 2012 (Poxviridae Infections...) : Consistent with this, C4 inhibited interleukin-1ß induced translocation of p65 into the nucleus
Byun et al., Biochem Biophys Res Commun 2012 (Inflammation) : In addition, EGCG treated DCs inhibited lipopolysaccharide (LPS) induced production of pro-inflammatory cytokines ( tumor necrosis factor [TNF ] -a, interleukin [ IL]-1ß, and IL-6 ) and activation of mitogen activated protein kinases ( MAPKs ), e.g., extracellular signal regulated kinase 1/2 ( ERK1/2 ), p38, c-Jun N-terminal kinase (JNK), and nuclear factor ?B ( NF-?B ) p65 translocation through 67LR