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GJA1 — WNT1
Text-mined interactions from Literome
Ai et al., J Clin Invest 2000
:
Wnt-1 regulation of
connexin43 in cardiac myocytes
Du et al., Cell communication & adhesion 2008
:
Lithium chloride
regulates connexin43 in skeletal myoblasts in vitro : possible involvement in
Wnt/beta-catenin signaling
van der Heyden et al., J Cell Sci 1998
(Carcinoma, Embryonal) :
Also, induction of
Wnt1 expression in a mammary epithelial cell line
leads to an increase in gap-junctional communication and
Cx43 protein expression ... In transient transactivation assays in P19 EC cells we found that
Wnt1 and Li+, an ion that mimics Wnt signalling,
increased transcription from the rat
Cx43 promoter, potentially via TCF/LEF binding elements, in a pathway separate from cAMP induced Cx43 transactivation ... The results demonstrate that Cx43 acts as a functional target of Wnt1 signalling, and
Cx43 expression can be
regulated by
Wnt1 at the transcriptional level