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IL3 — SELP

Text-mined interactions from Literome

Tsuji et al., J Leukoc Biol 1994 (Inflammation...) : Furthermore, interleukin-1 (IL-1) and interferon-gamma (IFN-gamma) induced surface expression of P-selectin on platelets in the presence of a low concentration of thrombin and consequently enhanced their adhesion capacity to leukocytes
Khew-Goodall et al., Blood 1996 (Inflammation) : IL-3 induced cell-surface P-selectin expression in two phases ... The level of P-selectin expression induced by IL-3 added for 48 hours was similar to that induced by treatment of HUVEC for 10 minutes with thrombin, and the effect of adding IL-3 for 48 hours followed by thrombin for 10 minutes was additive ... Induction of cell-surface P-selectin expression by IL-3 was blocked by pretreatment of EC with a blocking monoclonal antibody against the IL-3 receptor alpha-chain ... Lipopolysaccharide (LPS), tumor necrosis factor alpha (TNF alpha) and a mutant form of IL-3 with decreased potency did not induce cell-surface P-selectin expression after 48 hours ' incubation with HUVEC, suggesting that the effect was specific to IL-3
Yao et al., J Exp Med 1996 : Tumor necrosis factor alpha, IL-1 beta, lipopolysaccharide, or IL-3 did not increase P-selectin mRNA in HUVEC, and did not augment the IL-4 induced increase in P-selectin transcripts