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BAIAP2 — RAC2

Pathways - manually collected, often from reviews:

• KEGG Adherens junction: RAC1/RAC2/RAC3 → Complex of BAIAP2-WASF1-WASF2-WASF3 (protein-protein, activation)
  
• KEGG Regulation of actin cytoskeleton: RAC1/RAC2/RAC3 → BAIAP2 (protein-protein, activation)
• WikiPathways Regulation of Actin Cytoskeleton: RAC1/RAC3/RAC2 → BAIAP2 (activation)

Text-mined interactions from Literome

Miki et al., Nature 2000 : From studies of ectopic expression, we found that IRSp53 is essential for Rac to induce membrane ruffling, probably because it recruits WAVE, which stimulates actin polymerization mediated by the Arp2/3 complex
Suetsugu et al., J Cell Biol 2006 : Purified WAVE2 and purified WAVE2 complex were activated by IRSp53 in a Rac dependent manner with PIP ( 3 ) -containing liposomes
Abou-Kheir et al., J Cell Sci 2008 : Membrane targeting of WAVE2 is not sufficient for WAVE2 dependent actin polymerization : a role for IRSp53 in mediating the interaction between Rac and WAVE2
Teodorof et al., Exp Cell Res 2009 : SPIN90 and IRSp53 positively cooperated to mediate Rac activation, and co-expression of SPIN90 and IRSp53 in COS-7 cells led to the complex formation of SPIN90-IRSp53 in the leading edge of cells