Gene interactions and pathways from curated databases and text-mining

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SETD2 — TLR7

Text-mined interactions from Literome

Gibbs et al., Int J Biochem Cell Biol 2012 (Congenital Disorders of Glycosylation...) : Furthermore, we observed that nitric oxide synthase activity was dependent on mTOR in these myeloid cells and involved in HIF-1a accumulation mediated by endosomal toll-like receptor 7/8 triggering in THP-1 cells as well as IgE dependent basophil, but not mast cell, responses
Shakespear et al., J Biol Chem 2013 (Inflammation) : Thus, Hdac7-u positively regulates HIF-1a dependent TLR signaling in macrophages, whereas an interaction with CtBP1 likely prevents Hdac7-s from exerting this effect