Gene interactions and pathways from curated databases and text-mining

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SLC17A5 — TIMP1

Text-mined interactions from Literome

Aoyama et al., Am J Nephrol 2000 (Diabetes Mellitus, Type 2...) : In conclusion, AST-120 reduced the interstitial expression of TGF-beta(1) and TIMP-1 , and the interstitial infiltration of macrophages, and ameliorates the progression of diabetic nephropathy in OLETF rats
Miyazaki et al., Nephrol Dial Transplant 2000 (Uremia) : AST-120 reduces the gene expression of TGF-beta1, TIMP-1 and pro-alpha1 ( I ) collagen in the kidneys, and delays the progression of CRF, at least in part, by alleviating the overload of indoxyl sulphate on remnant proximal tubular epithelial cells