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SLC17A5 — TIMP1
Text-mined interactions from Literome
Aoyama et al., Am J Nephrol 2000
(Diabetes Mellitus, Type 2...) :
In conclusion,
AST-120 reduced the interstitial expression of TGF-beta(1) and
TIMP-1 , and the interstitial infiltration of macrophages, and ameliorates the progression of diabetic nephropathy in OLETF rats
Miyazaki et al., Nephrol Dial Transplant 2000
(Uremia) :
AST-120 reduces the gene expression of TGF-beta1,
TIMP-1 and pro-alpha1 ( I ) collagen in the kidneys, and delays the progression of CRF, at least in part, by alleviating the overload of indoxyl sulphate on remnant proximal tubular epithelial cells