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SOCS2 — STAT1

Pathways - manually collected, often from reviews:

• KEGG Jak-STAT signaling pathway: STAT1/STAT2/STAT3/STAT4/STAT5A/STAT5B/STAT6 → SOCS1/SOCS2/SOCS3/SOCS4/SOCS5/SOCS7 (gene expression, expression)
  

Text-mined interactions from Literome

Shen et al., FEBS Lett 2000 : Injection of IL-10 into mice activated STAT3 but not STAT1 tyrosine phosphorylation and induced suppressor of cytokine signal 2 (SOCS2) , SOCS3, and cytokine-inducible SH2 protein (CIS) mRNA expression in the liver ... These findings suggest that IL-10 inhibits IFN-alpha activated STAT1 in the liver, at least in part, by inducing SOCS2 , SOCS3, and CIS expression, which may be responsible for the resistance of IFN-alpha therapy in patients who have high levels of IL-10 and recommends that IL-10 treatment for viral hepatitis should be cautious
Zimmerer et al., J Immunol 2007 : Overexpression of SOCS1 and SOCS3, but not SOCS2 , in the Jurkat T cell line inhibited IFN-alpha induced phosphorylated STAT1 and the transcription of IFN stimulated genes
Song et al., J Biol Chem 1998 : SOCS1 and SOCS3 but not SOCS2 inhibited the tyrosine phosphorylation and nuclear translocation of STAT1 in response to IFN stimulation