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HSP90AA1 — NOS2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Shah et al., Am J Physiol 1999
(Hypertension, Portal) :
Hsp90 regulation of endothelial
nitric oxide synthase contributes to vascular control in portal hypertension
Harris et al., Am J Physiol Heart Circ Physiol 2003
:
Endothelial
nitric oxide ( NO ) synthase ( eNOS ) is
regulated by
heat shock protein 90 (HSP90) , a heat-inducible protein ; however, the effect of heat shock on eNOS expression and eNO release is unknown
Yoshida et al., J Biol Chem 2003
:
Hsp90 , at physiological concentrations ( 10-500 nm ), dose-dependently
increased iNOS activity
Teng et al., J Biol Chem 2004
(Cell Transformation, Neoplastic) :
Heat shock protein 90 (HSP90) is
involved in the folding of proteins such as signal transduction molecules ( Src, Raf1, cdk4 ) and steroid receptors and in enhancing the activity of telomerase and
nitric-oxide synthase
Park et al., Free Radic Biol Med 2011
:
Chk1 and
Hsp90 cooperatively
regulate phosphorylation of endothelial
nitric oxide synthase at serine 1179
Lu et al., Life Sci 2012
(Myocardial Infarction...) :
The mechanism underlying EPO mediated alleviation of nitrosative stress was related to an increase in arginase II expression and to the suppression of
heat shock protein 90 (HSP90) dependent upregulation of endothelial and
inducible NO synthase ( NOS )
García-Cardeña et al., Nature 1998
:
Dynamic
activation of endothelial
nitric oxide synthase by
Hsp90