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IL6 — SERPINA6

Text-mined interactions from Literome

Fernandez-Real et al., J Clin Endocrinol Metab 2002 (Inflammation...) : Corticosteroid binding globulin (CBG) , the main plasma protein transport for cortisol, has been shown to be negatively regulated by insulin and IL-6 , at least in vitro, suggesting that insulin resistance and inflammation may both contribute to decreasing CBG levels
Emptoz-Bonneton et al., J Clin Endocrinol Metab 1997 (Hepatoblastoma...) : The present study investigated the effects of interleukin-6 (IL-6) , IL-1 beta, and dexamethasone on CBG synthesis by a clone of human hepatoblastoma derived ( HepG2 ) cell line ... However, in combination with IL-6, dexamethasone had a significant additive effect on IL-6 inhibition of CBG secretion and mRNAs in HepG2 cells ... In addition, IL-1 beta significantly decreased the inhibitory effect of IL-6 on CBG secretion, but had no effect on the inhibitory effect of IL-6 on CBG mRNA levels