Gene interactions and pathways from curated databases and text-mining

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CD40 — HLA-DRB1

Text-mined interactions from Literome

Rushworth et al., Transplantation 2002 : We have previously shown that binding of human CD154 expressed on the Jurkat D1.1 cell line to porcine CD40 on pig aortic endothelial cells ( PAECs ) can lead to up-regulation of vascular cell adhesion molecule (VCAM)-1 and MHC class II
Gutzmer et al., J Immunol 2003 : IL-18 strongly up-regulated CD54 on MoDC, whereas the effect on MHC class II , CD83, and CD86 was only moderate and the expression of CD40 and CD80 was not affected
Patel et al., J Clin Immunol 1995 : While activation of TE cells with IFN-gamma for 48 hr induced a greater than fivefold increase in the expression of four surface molecules ( CD38, CD54, MHC class I, and MHC class II ), it also induced a greater than 50 % increase in the expression of 14 other surface molecules ( CD12, CD29, CD40 , CD44, CD47, CD49b, CD49c, CD49e, CD55, CD66, CD87, CD104, TE4, and STE3 ) and a decrease in the expression of three molecules ( CDw65, CDw109, and STE2 )