Cordelier et al., J Biol Chem 2006
:
Regulation of neuronal nitric-oxide synthase activity by somatostatin analogs following SST5 somatostatin receptor activation ... SST5 mediated inhibition of nNOS activity was demonstrated to be essential to the RC-160 anti-proliferative effect on pancreatic endocrine tumor derived cells
Basivireddy et al., Biochem Pharmacol 2013
(Multiple Sclerosis) :
Furthermore, inflammation induced changes in extracellular signal regulated kinases ( ERK1/2 and ERK5 ) signaling and altered expression of endothelial and inducible nitric oxide synthase are modulated in presence of SST