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CASP6 — SPP1
Text-mined interactions from Literome
Graessmann et al., Oncogene 2007
(Mammary Neoplasms, Animal) :
In serum starved ME-A cells, the
OPN containing ME-C cell medium
prevents caspase-3 activation
Cuvillier et al., J Biol Chem 1998
:
Thus,
SPP , likely generated via protein kinase C-mediated activation of sphingosine kinase,
suppresses the apoptotic pathway downstream of FLICE but upstream of the executioner caspases,
caspase-3 , -6, and -7