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PDGFRB — SMC3
Text-mined interactions from Literome
Liu et al., FASEB J 2007
:
In summary, these results demonstrate that 5-HT transactivates
PDGFRbeta in PASMCs
leading to
SMC proliferation and migration, and may be an important signaling pathway in the production of PH in vivo
Lamy et al., Carcinogenesis 2008
(Neovascularization, Pathologic) :
The inhibitory effect of delphinidin on
PDGFR-beta was very rapid and
led to the inhibition of PDGF-BB induced activation of extracellular signal regulated kinase ( ERK)-1/2 signaling and of the chemotactic motility of SMC, as well as the differentiation and stabilization of EC and
SMC into capillary-like tubular structures in a three-dimensional coculture system
Fukai et al., Arterioscler Thromb Vasc Biol 2009
(Carotid Artery Injuries...) :
These results suggest the possibility that syndecan-1 may limit intimal thickening in injured arteries by suppressing
SMC activation through inhibition of SMC PDGF-B chain expression and
PDGFRbeta activation