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IL6 — RAG2

Text-mined interactions from Literome

Hillion et al., Autoimmun Rev 2007 (Autoimmune Diseases) : Peripheral expression of RAG in human B lymphocytes in normal and pathological conditions is dependent on interleukin-6
Hillion et al., Immunology 2007 (Lupus Erythematosus, Systemic) : Furthermore, IL-6 receptor blockade led to a reduction in p27 ( Kip1 ) expression, and allowed the translocation of RAG2 from the nucleus to the cytoplasm
Rochas et al., Arthritis Rheum 2009 (Arthritis, Rheumatoid...) : Transmembrane BAFF from rheumatoid synoviocytes requires interleukin-6 to induce the expression of recombination activating gene in B lymphocytes
Yan et al., J Autoimmun 2012 : Diminishing IL-6 by blocking antibody or haplo-insufficiency leads to reduced expression of the IL-7 receptor and RAG and increased titers of anti-DNA antibodies following immunization with a peptide mimetope of DNA
Muraguchi et al., Leukemia & lymphoma 1998 : Among the cytokines, IL-3, IL-6 , and IL-7, but not IL-2, IL-4, SCF, GM-CSF induces RAG activation