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Abrahams et al., Arthritis Rheum 2000
(Arthritis, Rheumatoid) :
This study suggests a dominant role for FcgammaRIIIA in the induction of both TNFalpha and IL-1alpha production by human macrophages in rheumatoid arthritis following receptor ligation by small immune complexes
Chouchakova et al., J Immunol 2001
(Alveolitis, Extrinsic Allergic...) :
These data suggest that in immune complex alveolitis, the activation of FcgammaRIII may induce divergent downstream effector pathways with TNF-alpha acting independently of CXC chemokines to trigger the inflammatory response in C57BL/6 mice