UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to YWHAZ

TOPBP1 — YWHAZ

Pathways - manually collected, often from reviews:

NCI Pathway Database ATR signaling pathway: YWHAZ (YWHAZ) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) (modification, activates)
Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database ATR signaling pathway: YWHAZ (YWHAZ) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN/CHK1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-CHEK1-TIMELESS-TIPIN) (modification, activates)
Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
Evidence: mutant phenotype, assay, physical interaction