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CD80 — NFKB1
Text-mined interactions from Literome
Zoog et al., Mol Immunol 2004
:
Upon cellular entry, Antp-CD40 activated
NF-kappaB dependent transcription, induced proteolytic processing of p100 to the p52/NF-kappaB2 subunit, and increased expression of
CD80 and CD54 on the surface of B cells
Giguère et al., J Virol 2004
:
Moreover, we demonstrate that
NF-kappaB is
induced by
CD80- and CD86 bearing virions when they are combined with the engagement of the T-cell receptor/CD3 complex, an event that is inhibited upon surface expression of CTLA-4
Zhu et al., Transplant Proc 2008
:
We undertook this study to determine whether CD154-CD40 interactions induced human endothelial cell ( EC ) activation via the nuclear factor (NF)-kappaB pathway, and whether the upregulation of monocyte derived CD40 and
CD80 is
NF-kappaB pathway
dependent ... The
NF-kappaB inhibitor
suppressed upregulation of monocytederived CD40 and
CD80
Yang et al., Biol Pharm Bull 2008
:
Activation of
NF-kappaB and ERK1/2 were
necessary for
CD80 , CD86 and MHCII expression induced by semi-vioxanthin
Yin et al., Zhonghua Zhong Liu Za Zhi 2008
(Liver Neoplasms, Experimental) :
H22-CD80/CD86/CD137L ( + )
induces higher
NF-kappaB activity of the host T cells by synergistic action of CD28 and CD137, which may be one of the mechanisms of enhancement of the host CTL activity induced by co-expression of CD80, CD86 and CD137L genes