Gene interactions and pathways from curated databases and text-mining

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CD80 — NFKB1

Text-mined interactions from Literome

Zoog et al., Mol Immunol 2004 : Upon cellular entry, Antp-CD40 activated NF-kappaB dependent transcription, induced proteolytic processing of p100 to the p52/NF-kappaB2 subunit, and increased expression of CD80 and CD54 on the surface of B cells
Giguère et al., J Virol 2004 : Moreover, we demonstrate that NF-kappaB is induced by CD80- and CD86 bearing virions when they are combined with the engagement of the T-cell receptor/CD3 complex, an event that is inhibited upon surface expression of CTLA-4
Zhu et al., Transplant Proc 2008 : We undertook this study to determine whether CD154-CD40 interactions induced human endothelial cell ( EC ) activation via the nuclear factor (NF)-kappaB pathway, and whether the upregulation of monocyte derived CD40 and CD80 is NF-kappaB pathway dependent ... The NF-kappaB inhibitor suppressed upregulation of monocytederived CD40 and CD80
Yang et al., Biol Pharm Bull 2008 : Activation of NF-kappaB and ERK1/2 were necessary for CD80 , CD86 and MHCII expression induced by semi-vioxanthin
Yin et al., Zhonghua Zhong Liu Za Zhi 2008 (Liver Neoplasms, Experimental) : H22-CD80/CD86/CD137L ( + ) induces higher NF-kappaB activity of the host T cells by synergistic action of CD28 and CD137, which may be one of the mechanisms of enhancement of the host CTL activity induced by co-expression of CD80, CD86 and CD137L genes