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IL33 — NLRP3
Text-mined interactions from Literome
Li et al., J Immunol 2008
(Inflammation) :
In this study we show that, in human and mouse macrophages, alum induced secretion of IL-1beta, IL-18, and
IL-33 is
mediated by the NLR ( nucleotide binding domain leucine-rich repeat containing ) protein
NLRP3 and its adaptor ASC, but not by NLRC4
Komune et al., J Virol 2011
:
Measles virus V protein inhibits
NLRP3 inflammasome
mediated interleukin-1ß secretion
Zhong et al., Nature communications 2013
:
Exposure to particulate crystals can induce oxidative stress in phagocytes, which triggers
NLRP3 inflammasome
mediated interleukin-1ß secretion to initiate undesirable inflammatory responses that are associated with both autoinflammatory and metabolic diseases