Gene interactions and pathways from curated databases and text-mining

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IL33 — NLRP3

Text-mined interactions from Literome

Li et al., J Immunol 2008 (Inflammation) : In this study we show that, in human and mouse macrophages, alum induced secretion of IL-1beta, IL-18, and IL-33 is mediated by the NLR ( nucleotide binding domain leucine-rich repeat containing ) protein NLRP3 and its adaptor ASC, but not by NLRC4
Komune et al., J Virol 2011 : Measles virus V protein inhibits NLRP3 inflammasome mediated interleukin-1ß secretion
Zhong et al., Nature communications 2013 : Exposure to particulate crystals can induce oxidative stress in phagocytes, which triggers NLRP3 inflammasome mediated interleukin-1ß secretion to initiate undesirable inflammatory responses that are associated with both autoinflammatory and metabolic diseases