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PTEN — SLC2A4

Text-mined interactions from Literome

Nakashima et al., J Biol Chem 2000 (MAP Kinase Signaling System) : PTEN overexpression inhibited insulin induced 2-deoxy-glucose uptake by 36 %, GLUT4 translocation by 35 %, and membrane ruffling by 50 %, all of which are phosphatidylinositol 3-kinase dependent processes, compared with uninfected cells or cells infected with control virus
Mosser et al., Biochem Biophys Res Commun 2001 (MAP Kinase Signaling System) : Since PI 3-kinase is required for many metabolic actions of insulin, we investigated the role of PTEN in insulin stimulated translocation of GLUT4 ... Overexpression of PTEN-CBR3 ( mutant with disrupted membrane association domain ) partially impaired translocation of GLUT4