Bhathena et al., Drug Metab Dispos 2002
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Our aim was to determine whether CYP2C11 suppression by AHs is mediated by the AHR via interaction with DRE-like sequences
Shaban et al., Xenobiotica 2005
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To the best of the authors ' knowledge, this is the first study showing the presence of mutual effects of AhR and PPARalpha on CYP2B and CYP3A and an additive inhibitory effect on CYP2C11 in the livers of male rats
Safa et al., Toxicol Lett 1997
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We performed a structure-activity relationship study with a series of PAHs of the anthracene class in order to determine if the AH receptor is involved in CYP2C11 down-regulation ... These results suggest that the AH receptor plays a role in the down-regulation of CYP2C11 caused by PAHs