Gene interactions and pathways from curated databases and text-mining

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FGF2 — HOXB9

Text-mined interactions from Literome

Curran et al., Dev Biol 2000 : Inhibition of FGF signaling does not block posterior neural gene expression ( HoxB9 ) or activation of MAPK ; however, inhibition of FGF signaling does cause a statistically significant decrease in the level of activated MAPK
Naora et al., Proc Natl Acad Sci U S A 2001 (Ovarian Neoplasms) : Furthermore, HOXB7 overexpression increased intracellular accumulation and secretion of basic fibroblast growth factor , a potent angiogenic and mitogenic factor ... Furthermore, HOXB7 overexpression increased intracellular accumulation and secretion of basic fibroblast growth factor , a potent angiogenic and mitogenic factor
Shiotsugu et al., Development 2004 : Overexpression of a constitutively active RARalpha2 rescues the effects of FGF blockade on the expression of XCAD3 and HOXB9
Hayashida et al., Proc Natl Acad Sci U S A 2010 (Breast Neoplasms...) : HOXB9 induces the expression of several angiogenic factors ( VEGF, bFGF , IL-8, and ANGPTL-2 ), as well as ErbB ( amphiregulin, epiregulin, and neuregulins ) and TGF-ss, which activate their respective pathways, leading to increased cell motility and acquisition of mesenchymal phenotypes