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PDK1 — SGK3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: SGK3 — PDK1 (colocalization, fluorescence microscopy) Slagsvold et al., EMBO J 2006*
• IRef Intact Interaction: SGK3 — PDK1 (phosphorylation reaction, protein kinase assay) Slagsvold et al., EMBO J 2006*

Text-mined interactions from Literome

He et al., Mol Biol Cell 2011 : Activation of SGK3 and NHE3 by Dex was dependent on phosphoinositide 3-kinase (PI3K) and phosphoinositide dependent kinase 1 ( PDK1 ), and Dex induced translocation of PDK1 to endosomes
Liu et al., Hepatology 2012 (Carcinoma, Hepatocellular...) : We also found that expression of SGK3 , which like AKT is activated by PI3K/PDK1 signaling, has more significance than overexpression of AKT in predicting poor outcome in HCC patients