Gene interactions and pathways from curated databases and text-mining

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OSM — TYK2

Text-mined interactions from Literome

Halfter et al., Mol Cell Biol Res Commun 1999 (Glioma) : While OSM induces a number of strong tyrosine phosphorylations, including Janus tyrosine kinases ( Jak ) and the signal transducer and activator of transcription ( Stat ) proteins, LIF induces only minor tyrosine phosphorylation of Tyk2 and Stat3
Chauhan et al., J Exp Med 1995 : In the present study using U266B1 human multiple myeloma cells, we show that OSM induces tyrosine phosphorylation and activation of JAK2, but not JAK1 or Tyk2 , kinases
Auguste et al., J Biol Chem 1997 : Both type I and type II OSM receptors activated Jak1, Jak2, and Tyk2 receptor associated tyrosine kinases