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OSM — TYK2
Text-mined interactions from Literome
Halfter et al., Mol Cell Biol Res Commun 1999
(Glioma) :
While
OSM induces a number of strong tyrosine phosphorylations, including Janus tyrosine kinases ( Jak ) and the signal transducer and activator of transcription ( Stat ) proteins, LIF
induces only minor tyrosine phosphorylation of
Tyk2 and Stat3
Chauhan et al., J Exp Med 1995
:
In the present study using U266B1 human multiple myeloma cells, we show that
OSM induces tyrosine phosphorylation and activation of JAK2, but not JAK1 or
Tyk2 , kinases
Auguste et al., J Biol Chem 1997
:
Both type I and type II
OSM receptors
activated Jak1, Jak2, and
Tyk2 receptor associated tyrosine kinases