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PCNA — WEE1

Text-mined interactions from Literome

Wroble et al., BMC developmental biology 2007 : One key event that occurs at the MBT is the degradation of maternal Wee1 , a negative regulator of cyclin dependent kinase (Cdk) activity
Li et al., Mol Cell Biol 2010 : RXL1 and T239 mutants each mediated greater Cdk phosphorylation and G ( 2 ) /M inhibition than the wild type, suggesting that cyclin A/Cdk complexes inhibit human Wee1 through these sites
Masuda et al., Mol Biol Cell 2011 : During the G2/M transition when cyclin B-Cdc2 is highly enriched at the SPB, Wee1 temporally accumulates at the nuclear face of the SPB in a cyclin B-Cdc2 dependent manner and locally suppresses both cyclin B-Cdc2 activity and spindle assembly to counteract a Polo kinase dependent positive feedback loop
Walter et al., Mol Biol Cell 1997 : Early MAP kinase activation did not interfere significantly with DNA replication, cyclin synthesis, or association of cyclins with Cdc2, but it did prevent hyperphosphorylation of Cdc25 and Wee1 and activation of Cdc2/cyclin complexes