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ASIC3 — NGF

Text-mined interactions from Literome

Mamet et al., J Biol Chem 2003 (Inflammation) : We previously showed that low endogenous NGF was responsible for ASIC3 basal expression and high NGF during inflammation increased ASIC3 expression parallely to the development of neuron hyperexcitability associated with hyperalgesia ... NGF controls ASIC3 basal expression through constitutive activation of a trkA/phospholipase C/protein kinase C pathway, ( ii ) ... high inflammatory-like NGF induces ASIC3 overexpression through a trkA/JNK/p38MAPK pathway and a p75 dependent mechanism as a transcriptional switch, and ( iii )
Uchiyama et al., J Bone Miner Res 2007 (MAP Kinase Signaling System) : Because studies of neuronal cells have shown that ASIC3 expression and promoter activity is induced by nerve growth factor (NGF) , we examined the effect of NGF on nucleus pulposus cells
Lu et al., J Appl Physiol 2012 (Anoxia) : However, NGF increased expression of ASIC3 in DRG neurons with C-fiber but not A-fiber