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IL13 — IL5
Text-mined interactions from Literome
Suchin et al., J Am Acad Dermatol 2001
(Eosinophilia...) :
Increased
interleukin 5 production in eosinophilic Sézary syndrome :
regulation by interferon alfa and
interleukin 12
Foster et al., Immunol Rev 2001
(Asthma...) :
Regulation of
IL-5 and eotaxin levels within the lung by IL-4 and
IL-13 allows Th2 cells to elegantly co-ordinate tissue and peripheral eosinophilia
Pope et al., J Allergy Clin Immunol 2001
(Pulmonary Eosinophilia) :
IL-5 is
required for
IL-13 to induce eosinophilia throughout the lung, whereas eotaxin regulates the distribution of airway eosinophils
Nielsen et al., Blood 2002
(Lymphoma, T-Cell, Cutaneous) :
Transfection of tumor cells with dominant negative Stat3 almost completely blocks
IL-5 production and strongly
inhibits IL-13 production, whereas IL-6 production is unaffected
Mattes et al., Curr Drug Targets Inflamm Allergy 2003
(Inflammation) :
Recent studies also indicate that
IL-5 and eotaxin, through eosinophils, may
regulate Th2 cell function and
IL-13 production from this lymphocyte
Yang et al., J Allergy Clin Immunol 2003
(Bronchial Hyperreactivity...) :
Eotaxin-2 and
IL-5 cooperatively
promoted eosinophil accumulation,
IL-13 production, and AHR to methacholine
Melk et al., Transplantation 2004
(Growth Disorders...) :
During rhGH therapy in children with transplants,
interleukin (IL)-2 production increased threefold at 4 weeks, and IL-4 and
IL-13 increased by 70 % at 12 weeks
Edwan et al., Immunol Res 2007
(Asthma) :
pUMVC3-hFLex treatment prevented the development of goblet cell hyperplasia and subepithelial fibrosis, and significantly reduced serum levels of IL-4 and
IL-5 , and
increased serum IL-10 levels ( p < 0.05 ) with no effect on serum
IL-13
Haber et al., Exp Parasitol 2009
(Hyperalgesia...) :
Leishmania major :
interleukin-13 increases the infection induced hyperalgesia and the levels of interleukin-1beta and
interleukin-12 in rats
Hammer et al., Microbiol Immunol 2008
:
Oil B inhibited the production of all cytokines except IL-10, oil X inhibited TNF-alpha, IL-6 and IL-10, oil A inhibited TNF-alpha and IL-6, oil C inhibited
IL-5 and IL-6 and oil Z
inhibited IL-13 only
Tweyongyere et al., BMC infectious diseases 2011
(Pregnancy Complications, Parasitic...) :
There was some evidence that maternal infection intensity was positively associated with cord blood IL-5 and
IL-13 responses to SWA, and
IL-5 responses to SEA, and that this association was modified by treatment with praziquantel
Higaki et al., Clin Exp Allergy 2012
(Eosinophilia...) :
LPS pre-treatment
enhanced SEB induced IL-5,
IL-13 and IL-17A production in diclofenac treated DNPCs, while addition of PGE ( 2 ) inhibited
IL-5 , IL-13 and IFN-? production ... LPS alone
induced IL-5,
IL-13 and IFN- ? production by diclofenac treated DNPCs, while the addition of EP2 and EP4 receptor-selective agonists, as well as PGE ( 2 ) itself, inhibited
IL-5 and IL-13 production
Swain et al., Proc Natl Acad Sci U S A 1981
:
We conclude that the C.C3.11.75
TRF activity is not
due to
interleukin 1 or to interleukin 2 but to a third factor provisionally designated as ( DL ) TRF
Zaitseva et al., Infect Immun 1995
:
Gamma interferon ( IFN-gamma ),
interleukin-2 (IL-2), IL-4, and
IL-5 induction was assayed by mRNA-specific PCR and by enzyme linked immunosorbent assay and bioassay for protein production
Ochensberger et al., Blood 1996
:
Furthermore, although some
IL-13 is produced in response to C5a in the
presence of
IL-5 , GM-CSF, IGF-1 or IL-1 beta, IL-3 is by far the most effective