Gene interactions and pathways from curated databases and text-mining

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CDK9 — MNAT1

Pathways - manually collected, often from reviews:

  • Reactome Reaction: CDK9 → MNAT1 (indirect_complex)
  • Reactome Reaction: CDK9 → MNAT1 (reaction)

Text-mined interactions from Literome

Zhou et al., J Biol Chem 2001 : TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription ... The presence of TFIIH in the HIV-1 preinitiation complex inhibits CDK9 phosphorylation
Yao et al., Mol Cell Biol 2002 : Activation of the Bur1-Bur2 cyclin dependent kinase complex by Cak1
Pei et al., Mol Cell Biol 2006 : The other CAK-Mcs6 , the kinase component of transcription factor IIH (TFIIH)-cannot activate Cdk9 ... A cdk9 ( T212A ) mcs6 ( S165A ) strain, in which neither Cdk9 nor Mcs6 can be activated by CAK , has a synthetic growth defect, implying functional overlap between the two CDKs, which have distinct but overlapping substrate specificities