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BMP2 — TFAP2A
Text-mined interactions from Literome
Luo et al., Proc Natl Acad Sci U S A 2003
:
We report experiments with Xenopus laevis, using both intact embryos and ectodermal explants, showing that the
transcription factor AP2alpha is positively
regulated by
bone morphogenetic protein ( BMP ) and Wnt signaling, and that this activation is an essential step in the induction of neural crest ( NC )
Kato et al., Life Sci 2009
:
BMP-2 increased not only mRNA and protein expressions of Dlx5 followed by inducing Osterix and BSP levels in a dose- and time dependent manner with an increase in Runx2, Msx2, AJ18, ALP and OC levels, but also
induced PPARgamma2 and
aP2 levels
Bhat et al., Dev Biol 2013
:
Low
Bmp activates expression of transcription factors
Tfap2a and Tfap2c in the lateral neural plate, thereby specifying neural crest fate