◀ Back to IGF1
IGF1 — LHCGR
Text-mined interactions from Literome
Hirakawa et al., Endocrinology 1999
:
A
role of
insulin-like growth factor I in
luteinizing hormone receptor expression in granulosa cells
Lagaly et al., Mol Cell Endocrinol 2008
:
Adiponectin decreased ( P < 0.05 ) insulin induced progesterone and androstenedione production as well as attenuated
IGF-I induced
LHR , CYP11A1, and CYP17A1 gene expression in theca cells. In contrast, adiponectin decreased ( P < 0.05 ) LHR mRNA abundance in granulosa cells but did not affect steroidogenic enzyme gene expression in granulosa cells. Adiponectin had no effect ( P > 0.10 ) on proliferation of large-follicle theca cells
Lou et al., Sci China C Life Sci 2000
:
IGF-I stimulated
LHR expression in CL. PGF ( 2alpha ) inhibited expression of IGF-IR and LHR
Luo et al., Sci China C Life Sci 2000
:
Meanwhile, it was observed that EGF promoted IGF-I mRNA expression, and in preovulatory follicles,
IGF-I stimulated
LHR mRNA expression
Kanzaki et al., Mol Cell Endocrinol 1994
:
Basic fibroblast growth factor induces
luteinizing hormone receptor expression in the
presence of
insulin-like growth factor-I in ovarian granulosa cells
Zhang et al., Biol Reprod 1998
(Leydig Cell Tumor) :
In the present study, we assessed the
effect of
IGF-I on
LH receptor (LHR) gene expression in an immortalized murine Leydig tumor cell line ( BLT-1 )