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BRCA1 — XIST
Text-mined interactions from Literome
Xiao et al., Cell 2007
(Mammary Neoplasms, Experimental) :
A previous report indicated that
BRCA1 colocalizes with and is
necessary for the correct localization of
XIST , a noncoding RNA that coats the inactive X chromosome ( Xi ) to mediate formation of facultative heterochromatin
Sirchia et al., PloS one 2009
(Breast Neoplasms) :
We provide evidence that in breast cancer cells
BRCA1 is
involved in
XIST regulation on the active X chromosome, but not in its localization as previously suggested, and that XIST can be unusually expressed by an active X and can decorate it