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INS — WNT4

Text-mined interactions from Literome

Liu et al., Adv Exp Med Biol 2010 (Diabetes Mellitus, Type 2) : Beta-catenin/TCF7L2 dependent Wnt signaling ( the canonical pathway ) is involved in pancreas development, islet function, and insulin production and secretion
Yoon et al., Genes Dev 2010 : Wnt signaling regulates mitochondrial physiology and insulin sensitivity
Heller et al., Am J Physiol Endocrinol Metab 2011 : Wnt-4 had no effect on glucose stimulated insulin secretion or insulin gene expression
Thieme et al., Mol Cell Endocrinol 2012 (Diabetes Mellitus, Experimental...) : Insulin induced Wnt3a, Wnt4 and Brachyury expression in a temporal- and stage-specific pattern ... Only blastocysts cultured with insulin reached the Wnt3a, Wnt4 and Brachyury expression levels of stage 2 in vivo blastocysts, indicating that insulin is required for Wnt3a, Wnt4 and Brachyury expression during gastrulation ... Insulin induced Wnt3a and Wnt4 expression preceded Brachyury
Palsgaard et al., J Biol Chem 2012 (MAP Kinase Signaling System...) : We find that Wnt stimulation leads to phosphorylation of insulin signaling key mediators, including Akt, GSK3ß, and ERK1/2, although with a lower fold stimulation and slower time course than observed for insulin