Gene interactions and pathways from curated databases and text-mining

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RAC1 — TGFB1I1

Text-mined interactions from Literome

Hetey et al., Exp Cell Res 2005 : The EGF induced lamellipodia were Rac dependent and overexpressed WT Hic-5, but not non-phosphorylatable Hic-5 inhibited Rac activation
Deakin et al., PloS one 2012 : Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA ... These data identify discrete roles for paxillin and Hic-5 in Rac1 and RhoA dependent cell adhesion formation and maturation ; processes essential for productive cell migration