Gene interactions and pathways from curated databases and text-mining

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Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Nowak et al., Biol Trace Elem Res 2003 : The inhibition of amidolytic plasmin activity by Zn2+ and Cu2+ was reduced in the presence of EDTA, histidine, or albumin
Chiangjong et al., Talanta 2012 : The data revealed that albumin , which is the known plasminogen binding protein, dramatically induced plasmin activity and crystal invasion, whereas other proteins had no significant effects as compared to the control
Gubler et al., Thromb Res 1993 : Inactive albumin ( isolated during the same purification procedure as P-A1, but without tissue factor inducing activity ) did not suppress protein C activation or increase plasminogen activator inhibitor-1 release
Machovich et al., Arch Biochem Biophys 1997 : Heat denatured albumin pretreated with plasmin decreases K ( M ) and increases k ( cat ) for both intact plasminogen and des ( 1-77 ) -plasminogen activation by tPA, yielding catalytic efficiencies in excess of 8 x 10 ( 3 ) M ( -1 ) s ( -1 ) and 2 x 10 ( 4 ) M ( -1 ) s ( -1 ), respectively