Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Rask-Madsen et al., Arterioscler Thromb Vasc Biol 2005 (Arteriosclerosis...) : Furthermore, the review summarizes studies that implicate PKC in promoting proatherogenic mechanisms or inhibiting antiatherogenic mechanisms, including studies of endothelial dysfunction ; gene induction and activation of vascular NAD ( P ) H oxidase ; endothelial nitric oxide synthase expression and function ; endothelin-1 expression ; growth, migration, and apoptosis of vascular smooth muscle cells ; induction of adhesion molecules ; and oxidized low-density lipoprotein uptake by monocyte derived macrophages
Cheng et al., Acta Pharmacol Sin 2009 (Hypertrophy) : We hypothesized that dispersed NADPH oxidase , protein kinase Cepsilon ( PKCepsilon ), early response gene (ERG), and matrix metalloproteinase 9(MMP-9) across the heart by isoproterenol ( ISO ) medication might be mediated by the endothelin ( ET ) - ROS pathway