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RASA1 — TSC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: TSC1 — RASA1 (physical association, two hybrid) Yasui et al., Mol Cell Neurosci 2007

Text-mined interactions from Literome

Li et al., Mol Cell Biol 2004 (Tuberous Sclerosis) : Analysis of TSC1 binding defective mutants of TSC2 shows that TSC1 is not required for the TSC2 GAP activity but may function as a regulatory component in the TSC1/TSC2 complex
Cao et al., J Biol Chem 2006 (Insulin Resistance...) : The physical association between the C terminus of TSC2 ( amino acids 1280-1499 ) and FoxO1 degrades the TSC1-TSC2 complex and inhibits GTPase activating protein activity of TSC2 toward Rheb
Vega-Rubin-de-Celis et al., Biochemistry 2010 : mTORC1 is regulated by the small GTPase Rheb, which in turn is regulated by the GTPase activating protein complex, TSC1/TSC2