Dugas et al., Neuron 2010
:
miR-219 directly represses the expression of PDGFRalpha , Sox6, FoxJ3, and ZFP238 proteins, all of which normally help to promote OPC proliferation
Silber et al., PloS one 2012
(Cell Transformation, Neoplastic...) :
miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis